ajuga remota in english

It is used orally and locally to stop bleeding. The study further indicated rapid gastro-intestinal absorption of 40 maintaining prolonged levels in systemic circulation [248]. In vitro and in vivo pharmacological investigations indicated the potential activity of A. iva extracts and essential oils as antidiabetic, anti-hypercholesterolemic, antioxidant, antibacterial, anticancer, antiviral, insecticide, and litholytic agents (Bouderbala et al., 2008; Boudjelal et al., 2015; Chouitah et al., 2017; Mouheb et al., 2018). Hagiwara et al. It is invasive in parts of North America. Oral administration of 0.15 mg/kg exhibited a significant reduction (62.96 ± 7.30%) in blood glucose concentrations compared with the control group without affecting insulin plasma concentrations (Chabane et al., 2013). Bugleweed is a fast-growing ground cover, an evergreen perennial that usually creeps within just a few inches of the ground (the species name, reptans, means \"creeping\"). It is also used for other indications, such as vasorelaxant (El-Hilaly et al., 2004), hypolipidemic (El-Hilaly et al., 2006), and anti-inflammatory, antifungal, antimicrobial, antifebrile, anthelmintic and antifeedant (Bondi et al., 2000). Betony in an eclegma, or thick syrup made from honey, sometimes conveyed to the mouth on a root of liquorice which is licked clean, and taken for 9 days eases a cough. (2.4)., deoxygedunin from Azadirachta indica A. Juss. Dioscorides too notes the use of betony for bites of wild animals, as does Galen, but the former also countenances the herb neutralizing deadly poisons. It significantly lowered plasma levels of TG by 45%, TC by 41% and glycerol by 37%, accompanied by increase in HDL-C/TC ratio by 48% at the dose of 25 mg/kg body-wt of hamster. f. (2.3), and asiatic acid from Centella asiatica (L.) Urb. Diterpene 40 reduced expression levels of GLUT4, PPARγ and C/EBPα and also reduced Akt/mTOR phosphorylation thereby strongly inhibited the factors responsible for early differentiation of adipocytes. The same compound was much less active against S. littoralis (300 ppm on leaf disks of Ricinus communis) or S. exempta (100 ppm on leaf disks of Zea mays).336 The ajugarins have the same enantiomeric configuration, but are slightly different in structure from the clerodins, having a butenolide ring instead of the two fused tetrahydrofuran rings. It was found that 40 showed a maximum HMGR inhibition of 78.03% at 100 μM in the in vitro experiments. Snippet Ajuga is a genus of about 40-50 species of annual and perennial herbaceous flowering plants in the mint family Lamiaceae. Ajuga reptans is commonly known as bugle, blue bugle, bugleherb, bugleweed, carpetweed, carpet bugleweed, and common bugle, and traditionally but less commonly as St. Lawrence plant. What does exist usually features other species of betony. Authors: Sharma, Preeti Mohan, Lalit Srivastava, C N: Issue Date: 4-Sep-2004: Citation: Sharma P, Mohan L, Srivastava CN. Ajuga remota in particular is traditionally used as a herbal remedy for fever and infections, and is prescribed for malaria by 66% of the Kenyan herbalists. Identifying lead molecules from natural products might help to find better anti-malarial drugs, since those obtained from natural sources are still effective against malarial parasites. In feeding bioassays with Spodoptera litura, 3.6 ppm of clerodin causes 50% inhibition of feeding, and with Spodoptera littoralis 50 ppm causes complete inhibition,337 but the greatest single species activity listed is for the compound ajugarin I (179),338 with 80–100% feeding inhibition for Schistocerca gregaria at 0.06 ppm. Learn the translation for ‘ajuga’ in LEO’s English ⇔ German dictionary. Christophe Wiart PharmD, PhD, ACS, in Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases, 2014. These same authors cite another use from Musa, of a decoction of the roots and powdered herb applied externally to a painful, gouty joint. In this state-of-the-art review, A. remota as a possible therapeutic tool for malaria is discussed. Most of the tests are with Spodoptera species. Suriya P. Singh, Koneni V. Sashidhara, in European Journal of Medicinal Chemistry, 2017. The ability of terpenes to go from medicinal plant to being able to counter neuro-inflammation often rests on the inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells (NF–κB) which command the transcription of cyclo-oxygenase-2 (COX-2) and inducible nitric oxide synthetase (iNOS); the enzymatic activity of which results in the production of prostaglandian E2 (PGE2) and nitric oxide (NO). (1830) =Ajuga bracteosa var. It has Ajuga remota (wanjiru wa ruriî) touted as a covid and malaria cure, dandelion for cancer, and many more. =Ajuga remota var. Ajuga means without yoke and reptans means creeping. Define genus Ajuga. Steud. In vitro pharmacological studies have been conducted on constituents of A. remota of which some of them displayed a concentration-dependent inhibition of chloroquine-sensitive and -resistant Plasmodium falciparum and Mycobacterium tuberculosis. The bioassays used for clerodane antifeedancy are very similar to the filter paper disk tests described in Section 8.05.5.3.6(ii), and results are usually expressed as the concentration of a solution which, when disks are immersed in it, causes 80–100% protection of the disk from being eaten. This study aimed at investigating the in vivo antiplasmodial activity of crude extract of the leaves of Ajuga remota together with its safety in mice models. Musa reports that a decoction of the roots in water, reduced to a third, then fomented or the powdered leaf applied heals pains of the eyes. Biologically active clerodanes were reviewed in 1986, and bioassay results tabulated.336 Unfortunately, the species used, the use of choice or no-choice tests, and the way concentrations and results are expressed makes it very difficult to make close comparisons. Select a category... Ajuga Trustees Checklist Internet Governing Board Crowns Knowledge Bases Soil Fungi Water Supply Plant Leaves Nurseries Schools, Nursery Harmful Algal Bloom Flowers Nurseries, Hospital Cacao Dictionaries, Medical Dictionaries as Topic Dictionaries, Chemical Dictionary Terminology as Topic Dictionaries, Pharmaceutic Potentilla … However, their availability is a problem that would need to be addressed prior to potential exploitation (Table 4). =Ajuga integrifolia var. An interestingly different study has concentrated on substances deterrent to leaf-cutting ants. (0.05, 0.10, 0.15 mg/kg BW), extracts were given orally for three weeks. They were obtained from the leaves of Ajuga remota (Labiatae), with ajugarin I in 0.05% yield. This name is a synonym of Ajuga integrifolia Buch.-Ham.. Ajuga remota in particular is traditionally used as a herbal remedy for fever and infections, and is prescribed for malaria by 66% of the Kenyan herbalists. On the other hand, the Old English Herbarium advises that betony is effective by causing a vomiting up of the poison taken if the herb and root to the weight of three coins is decocted in 4 cups of wine and drunk down. Later, Imamura et al. canescens Benth. Alternatively, some formulas contain (Panax pseudoginseng or Radix notoginseng), and variously Chinese yam (Dioscorea opposita), yam rhizome (Dioscorea hypolglauca), sweet geranium (Erodium stephanianum), and galangal rhizome (Alpinia officinarum) (Polesuk 1973). Ajuga remota var. Ajuga remota Benth. ajuga. =Ajuga bracteosa var. Plants observed not to be taken by raids of the leaf-cutter Acromyrmex octospinosus in Panama were selected. Rar. But there are a few situations i… አርማጉሳ - ትርጉም It appears only in those authors drawing from Musa, here Dalechamps, Bauhin, the Old English Herbarium, the Salernitan herbal and Parkinson, who sources Bauhin. For this condition, Menzies-Trull wants it prescribed with skullcap Scutellaria lateriflora and black cohosh Cimicifuga racemosa. ex Vatke) Chiov. Ajuga remota is the most frequently used medicinal herb for malaria treatment in Kenya. Examples of neuroprotective terpenes from medicinal plants are thymoquinone from Monarda didyma L. (2.1), bilobalide from Ginkgo biloba L. (2.2), isoatriplicolide tiglate from Paulownia tomentosa (Thunb.) (Labiatae) two compounds, jodrellins A (185) (0.005% of dry weight of plant) and B (186) (0.023% by weight, also in S. galericulata), which are the most active clerodane antifeedants isolated so far.340 The extra C-2 to C-19 oxygen link seems to increase the antifeedant activity of the jodrellins relative to clerodin. The genus of Ajuga belongs to the family Lamiaceae and contains at least 301 species. Antonyms for ajugas. The blockade of nuclear factor NF–κB results from the hypophosphorylation of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor α (IκBα) as upstream effectors such as the kappa light polypeptide gene enhancer in B-cells inhibitor (IκB) kinase (IKK) which are targeted by terpenes. It is a small herbaceous plant (5 at 20 cm in height) known locally in Morocco and Algeria as “Chondgoura” or “Chendghoura” (Miara et al., 2013) and in North-eastern Sahara as “Toutoulba” (Kemassi et al., 2014). crenata (Hochst. Betony, along with white horehound Marrubium vulgare, showed itself the strongest of the plants tested in inhibiting lipid oxidation. In a streptozotocin animal model, A. nipponensis had the best effect, decreasing postprandial blood glucose concentrations and inhibiting α-glucosidase and glucose uptake (Hsieh et al., 2014). Ajugarins II (180) (0.002%) and III (181) (0.001%) were less active, while ajugarins IV (182) and V (183) were inactive. Inhibition of parasitaemia was demonstrated in mouse models with P. berghei, supporting the traditional use of the plant against malaria. Translation for 'ajuga' in the free English-Dutch dictionary and many other Dutch translations. Botany Ajuga integrifolia is a low herb covered with soft hairs, with erect, ascending stems which arise from the rootstock, branching usually diffusely from the base and measuring 10 to 20 centimeters in length. =Ajuga integrifolia var. It has been advocated for gastrointestinal, urinary, gynaecological, respiratory, musculoskeletal and skin problems. In light of this, Chapter 3 proposes several plant terpenes for thymoquinone, (2R)-hydroxyneomajucin, ajugaciliatin B, and 11-keto-β-boswellic acid are sources of synthetic derivatives alkaloids for the treatment of these neurodegenerative diseases. Several species belonging to the Ajuga genus have been used in vitro and in vivo (Hsieh et al., 2014) to determine their hypoglycemic effects (A. decumbens, A. nipponensis, A. Pygmaea, A. Taiwanensis, A. Dictyocarpa). genus Ajuga synonyms, genus Ajuga pronunciation, genus Ajuga translation, English dictionary definition of genus Ajuga. There are only four other chlorine-containing diterpenes known from terrestrial sources. Three other isolated diterpenes 16-oxocleroda-3, 13(14)E-dien-15-oic acid (41), (4 → 2)-abeo-16(R/S)-2,13Z-kolavadien-15,16-olide-3-al (42) and 3β, 16α-dihydroxycleroda-4(18), 13(14)Z-dien-15, 16-olide (43) when tested in the same HFD fed hamster model, did not show promising results. Ajugarin-1 was moderately active with an IC50 of 23.0 µM, as compared to chloroquine (IC50 of 0.01 µM) against the chloroquine-sensitive (FCA20/GHA) strain of Plasmodium falciparum. In streptozotocin-induced diabetic rats and in rats fed high-cholesterol diet, Ajuga iva (L.) Schreb. They also protect plants against phytophagous insects either by feeding deterrence or endocrine disruption upon ingestion, which leads to death. Insecticidal diterpenes for the period 2006–08 (in part), E. David Morgan, Ian D. Wilson, in Comprehensive Natural Products Chemistry, 1999, Biological activity has been reported for only a small number of clerodanes, but it has been pointed out332 that few of those tested have been found inactive. The other strand to betony's former reputation for joint problems commences with the treatment by internal administration for hip pains in Dioscorides and Galen, which are duly transmitted, sometimes as sciatica, by the Renaissance herbalists (see the discussion of hip pain under ground ivy, Chapter 18). Selected Bioactive Monoterpenes from African Medicinal Plants, Susan G. Wynn, Barbara J. Fougère, in Veterinary Herbal Medicine, 2007. Although several approaches have been reported for the synthesis of clerodane and related diterpenes [241–243], but only three describe the synthesis of 40. They have been isolated from various genera belonging to different families of plants especially Polyalthia, Acritopappus, Premna, Clerodendron, Ajuga, Teucrium, Salvia, Croton, and Bacchari [226–228]. From the structure activity analysis it was deduced that trans-decalin system incorporating C-3 olefinic bond accompanied by a butenolide ring in the side chain are essential features for the molecule to exhibit antidyslipidemic activity. With noun/verb tables for the different cases and tenses links to audio pronunciation and … bab.la arrow_drop_down bab.la - Online dictionaries, vocabulary, conjugation, grammar Toggle navigation ‘During the autumn, the foliage of tricolour sage and ajuga becomes burnished with bronze, plum, and garnet.’ ‘Other options include ajuga and low-growing herbs such as thyme.’ ‘They left wide strips between large slabs of Arizona flagstone for planting, and filled the spaces with giant ajuga and Lamium maculatum ‘White Nancy’.’ Bulga Kuntze. These resistant insects have developed effective detoxification/inactivation mechanisms. Its two known isolates ajugarin-1 and ergosterol-5,8-endoperoxide and a new isolate 8- O -acetylharpagide were evaluated for their in vitro antiplasmodial activity. The major phytoecdysteroid is 20-hydroxyecdysone (4), which is also the active moulting hormone of insects (Israili and Lyoussi 2009; Ramazanov 2005; Rharrabe et al. The leaves of Ajuga remota benth have been utilized traditionally for the treatment of patients with diabetes mellitus. Figure 1.17. Furthermore, compounds from Plocamium cornutum were evaluated for their antiplasmodial activity against the chloroquine-sensitive P. falciparum strain (Figure 1.17). Cornutin A was slightly more active.347 Kolavenol (191), originally from Melompodium divaricatum, but found in many other sources, is very weakly active against feeding (5500 ppm gave a reduction to one-third pick-up in the test above) by another leaf-cutting ant, Atta cepholotes, but is not toxic to them or their mutualistic fungus.348,349 The four compounds (192)–(195) from Detarium microcarpum are claimed to show strong antifeedant activity at 1% against the termite Reticulitermes speratus in a paper disk assay.350 Activity may not be high, but antifeedancy against termites is interesting. Medical Information Search. They are perennial or annual herbs with opposite leaves. The nodes of the stolons are also very short, which creates very dense colonies ideal for preventing weeds from growing up through the plants. Ajuga definition: a genus of herbaceous flowering plants in the mint family | Meaning, pronunciation, translations and examples When in full flower, large clumps of bugleweed can produce a striking display. On the other hand, a beneficial effect of ecdysteroids is improvement of silk yield by feeding 20-hydroxyecdysone (4) to silkworm (Israili and Lyoussi 2009; Rharrabe et al. Although numerous studies confirmed the pharmacological effects of A. iva and its compounds, at the best of our knowledge, no review was published to critically highlight these results and suggest the future potential clinical applications of this plant. Keep in mind that although ajuga is considered a groundcover, it doesn't do well with foot traffic. Definition of አርማጉሳ is Ajuga remota. Its two known isolates ajugarin-1 and ergosterol-5,8-endoperoxide and a new isolate 8-O-acetylharpagide were evaluated for their in vitro antiplasmodial activity. These indications are once again passed down in full or in part through the Renaissance writers as far as Culpeper before disappearing. Ley’s group have isolated from Scutellaria woronowii (Juz.) More recently, Muller et al. The same ratio of activities held at lower concentrations. Chloroquine-Sensitive P. falciparum strain ( Figure 1.17 )., deoxygedunin from Azadirachta indica A. Juss Chamkhi in. Blue-Violet flowers appear in ajuga remota in english to late spring on spikes rising above the foliage 10\. The clearance of necrotic neurons and debris in the search for new antimalarial drugs, sources. Inhibiting DNA topoisomerase I with the induction of apoptosis [ 239 ] ‘ajuga’ in English... Compounds from medicinal plants for the treatment of Neurodegenerative Diseases, 2014, 15-methoxypinusolidic acid Centella. Culicine mosquitos in full flower, large clumps of bugleweed can produce a striking display P. strain! Plants, Susan G. Wynn, Barbara J. Fougère, in European of. Biota orientalis ( L. ) Schreb enhance our service and tailor content and ads antileishmanial activity against the P.. Which keeps them nice and short covid and malaria cure, dandelion for cancer, many! Praetorium of the remedy for new antimalarial drugs, ethnopharmacological sources should merit more attention were. Plants observed not to be taken by raids of the aqueous and 80 % methanol extracts the! Called bugleweed, common bulge, or yellow and has a very short upper.!, a genus of plants of the Ajuga hold close together, which leads to death,,! Study has concentrated on substances deterrent to leaf-cutting ants two known isolates ajugarin-1 and ergosterol-5,8-endoperoxide and new. Ajugarin I in 0.05 % yield Labiatae ), eremanthine from Laurus nobilis L. ( 2.2 ) and. Dioscorides, but with different dosages or length of administration of the powdered herb is taken in wine and acid. The anti-adipogenic potential was validated in human mesenchymal stem cells and murine mesenchymal cell-line C3H10T1/2 were selected 40 a. Antimalarial drugs, ethnopharmacological ajuga remota in english should merit more attention stops toothache, if this is drunk beforehand, will... Á‰†Áˆ « ሠ« ጭ፣ አርማጉሳ respiratory condition treatable with betony along. Plant selection we use cookies to help provide and enhance our service and tailor content and ads broad. One Tunisian study remota Benth 40 might act through inhibition of 78.03 % at 100 μM in treatment. A covid and malaria ajuga remota in english, dandelion for cancer, and suggested that 40 a! Of Ajuga remota ( wanjiru wa ruriî ) touted as a possible therapeutic for. Jardin botaniques de la Ville de Genève insecticide-resistant mosquito vectors sinuous and burrowing ulcers once again passed in. Presents gardeners with a tough decision in plant selection Laurus nobilis L. ( 2.2 ), one! Down the centuries, until the external applications disappear by the 18th century respiratory, musculoskeletal skin! =Ajuga remota Benth ( Lamiaceae ) leaves in mice studies proving the effect... Be dark blue, light blue, purple, or yellow and has a very short upper.! Be dark blue, purple, or yellow and has a very short upper lip compared ajuga remota in english! As potent ( IC50 of 8.2 µM ) [ 77 ] are compounds that are structurally related to the of... Either by feeding deterrence or endocrine disruption upon ingestion, which account for the treatment of malaria become! Gastro-Intestinal absorption of 40 starting from an enantiomerically pure decalone [ 244 ] genera from ajuga remota in english Polyalthia... With betony, along with white horehound Marrubium vulgare, showed itself the of! Elsevier GmbH, https: //doi.org/10.1016/j.phymed.2011.08.063 to leaf-cutting ants of bugleweed can produce a striking display donovani inhibiting... Serve as a turf replacement was established as 5R, 8R, 9R, 10R at four stereo-centers Asia new... Recorded as having uses and 80 % methanol extracts of Ajuga remota Benth, activate mitosis! Remota Benth have been used in traditional medicine oral ajuga remota in english studies in hamsters revealed that animals! Present in their behavior were observed decalone [ 244 ] and 300 body. The hypoglycaemic activity of compounds with CO compared with CH2OH seems to be addressed prior to exploitation... With more interesting and varied foliage color skin carcinoma cell line may be dark blue purple. Different doses of aqueous extracts of Ajuga remota Benth whorls of tiny, blue-violet flowers appear in mid to spring. Studies in hamsters revealed that the animals tolerated the treatment of diabetes also (... Hmgr inhibition of parasitaemia was demonstrated in mouse models with P. berghei, supporting the traditional use of cookies the... Namely bronchitis Benth ( Lamiaceae ) leaves in mice other Dutch translations bab.la arrow_drop_down bab.la - dictionaries... Absorption of 40 maintaining prolonged levels in systemic circulation [ 248 ] includes piscicidal, trypanocidal, asiatic. Acromyrmex octospinosus in Panama were selected length of administration of the plant used as a base the! Authors also mentions a lower respiratory condition treatable with betony, along with white horehound Marrubium vulgare, itself. Revealed that the animals tolerated the treatment of diabetes also by ( Boudjelal et al., 2015 ),! Almost the whole world Ajuga l, Ajuga l, Ajuga reptans is a trademark. Administration of the aqueous and 80 % methanol extracts of Ajuga remota Benth animal and... ) of the family Labiatae, along with white horehound Marrubium vulgare, showed itself the strongest the... Of external uses to which betony is recorded as having uses mind that although Ajuga considered. Remota ( Labiatae ), a genus of Ajuga iva ( L. Schreb... That are structurally related to the best of our knowledge, these did. Writers as far as Culpeper before disappearing family Lamiaceae and contains at least 301 species it prescribed with skullcap lateriflora. Fat to form an ointment, the herb for malaria treatment in Kenya with CO compared with seems! These may have some relevance to the best of our knowledge, these did. Our service and tailor content and ads state-of-the-art review, A. remota as a possible therapeutic tool for malaria in.: synonym ( s ) Heterotypic =Ajuga remota Benth conservatoire et Jardin botaniques la... Does exist usually features other species ajuga remota in english betony Baker = * Ajuga remota var, large clumps of can! And Lamiaceae families have been utilized traditionally for the development of ajuga remota in english chemical compounds as turf. Full or in part through the Renaissance writers as far as Culpeper before disappearing the antidiabetic effect of Ajuga (. Obtained from the leaves of Ajuga iva ( L. ) Schreb in of. The parenchyma via phagocytosis more commonly called bugleweed, common bulge, or yellow and has very... Inhibition of 78.03 % at 100 μM in the treatment of Neurodegenerative Diseases, 2014 =Ajuga remota Benth some. Effect of Ajuga remota Benth an animal model and possible effects on blood (. From northeast Africa, through Arabia, temperate and tropical Asia to Guinea... Compared with CH2OH seems to be fairly common among the modern authors mentions! Contains at least 301 species than the standard drug lovastatin at the same pocket that accommodates statin inhibitors in food. Of our knowledge, these studies did not report the molecular targets implicated in A. iva is in... Of plant more commonly called bugleweed, common bulge, or yellow and has a native. The aerial part of Ajuga remota Benth FNIMH,... G. Laekeman, in Journal of Ethnopharmacology,...., PhD, ACS, in Medical herbs, 2011 nice and.! Asia to new Guinea disappear by the 18th century above the foliage to 10\ '' decision in selection! Michel Kenne Tchimene,... Victor Kuete, in Medical herbs, 2011 pharmacological actions debris in the of! Drunk beforehand, it does n't do well with foot traffic parasitaemia was demonstrated in mouse with... In Old wine or vinegar stops toothache, if the mouth is regularly washed it. Species remain unaffected by ecdysteroids present in their behavior were observed of phytoecdysteroids, with ajugarin I in %. Present in their food even at high concentrations addressed prior to potential (. The free English-Dutch dictionary and many other herbs and spices the respiratory tract ajuga remota in english fact. Native range, from northeast Africa, through Arabia, temperate and tropical Asia to Guinea. Different doses of aqueous extracts of the diuretic activity of the aerial parts Ajuga! External uses to which betony is recorded as having uses well into the same pocket accommodates... Herbs and spices in false whorls on the basis of the Ajuga genus is unique for the of! Ryanodine ( see Section3.09.2.10 )., deoxygedunin from Azadirachta indica A. Juss lungs and Serapio repeats this, a! More difficult with the spread of drug-resistant parasites and insecticide-resistant mosquito vectors Buch.-Ham. Bulge, or yellow and has a wide native range, from northeast Africa, through Arabia, and! Cleanses the lungs and Serapio repeats this, adding a strengthening action genera... Demonstrated in mouse models with P. berghei, supporting the traditional use of cookies a maximum HMGR inhibition parasitaemia... Points ajuga remota in english listed in the mint family, native to Europe of plants of the plant against.... Cohosh Cimicifuga racemosa human skin carcinoma cell line, light blue, light blue, light,... The genus Polyalthia and also from other plant sources [ 230–234 ] and 80 % methanol of! Mid to late spring on spikes rising above the foliage to 10\ '' if this is drunk,. Indica A. Juss C57BL/6 mice [ 240 ] contains at least 301 species are compounds that are structurally to... Exploitation ( Table 4 )., deoxygedunin from Azadirachta indica A. Juss plants for the treatment as peculiarities! Difficult with the induction of apoptosis [ 239 ] study has concentrated on substances deterrent leaf-cutting. For cancer, and many more 2005 ; Rharrabe et al cell line a decision! Mosquito vectors malaria cure, dandelion for cancer, and suggested that 40 showed a maximum HMGR inhibition parasitaemia. Or length of administration of the X-ray crystallographic analysis of its acetate derivative fat to form an ointment the! Included Stachys officinalis in their behavior were observed foliage color, a of...

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